Essentially, all models are wrong, but some are useful.
--- George E. P. Box (1987)

Eichler Lab

Department of Genome Sciences,
University of Washington

PingHsun (Benson) Hsieh

Postdoctoral Fellow
Office Phone: (206) 685-7336
Office Location: S433D
Email: hsiehph [AT]

Professional Experience

Postdoctoral Fellow
Dept. Genome Sciences, U. Washington, Seattle, WA, USA
Statistical Geneticist
Oregon Clinical and Translational Research Institute, OHSU, OR, USA


Ph.D., Ecology and Evolutionary Biology
University of Arizona, Tucson, AZ, USA
M.S., Computational Molecular Biology University of Southern California, Los Angeles, CA, USA 2008
M.S., Electrical Engineering National Taiwan University, Taiwan 2005
B.S., Computer Science and Information Engineering National Central University, Taiwan 2002

Research Interests

My research interests lie in the broad areas of evolution. I am particularly interested in developing new computational and statistical methods to study the evolution of human and nonhuman primates. Currently, I am studying methods for more accurately genotyping copy number variation of duplicated genes and gene families within human and great ape genomes. The goal is to understand the origin and the evolution of duplicated genes as well as their roles in human diseases, such as intellectual disability.

Selected Publications

Hsieh et al. Whole-genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection.Genome Research 26.3 (2016): 279-290.

Hsieh et al. Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies. Genome Research26.3 (2016): 291-300.